DENALI THERAPEUTICS H-1B Visa Sponsorship & Salary Data

The median H-1B salary at DENALI THERAPEUTICS is $138,000, based on 45 certified filings from FY 2020 to FY 2026. This is 15% higher than the national H-1B median salary of $120,000. Compensation at DENALI THERAPEUTICS reflects their market positioning, with entry-level roles starting around $123,000 and senior positions reaching $209,000 or higher. These figures represent base salaries in LCA filings and may not include bonuses, equity grants, or other compensation common at large employers.

Salaries at DENALI THERAPEUTICS range from $109,438 at the 10th percentile to $209,000 at the 90th percentile, showing a $99,562 spread across experience levels and roles. The 25th percentile is $123,000 and the 75th percentile is $165,333.

Yes, DENALI THERAPEUTICS actively sponsors H-1B visas in FY 2026. In the most recent fiscal year (FY 2026), DENALI THERAPEUTICS filed 5 H-1B labor condition applications with 4 certified and 0 denied, at a median salary of $138,000. Across FY 2020–2026, they have filed 49 total H-1B applications with 45 certified and a 0% lifetime denial rate, demonstrating ongoing commitment to hiring international talent. DENALI THERAPEUTICS sponsors positions across multiple job categories and locations, making them a viable option for professionals seeking H-1B visa sponsorship.

In the most recent fiscal year (FY 2026), DENALI THERAPEUTICS filed 5 H-1B applications, with 4 certified and 0 denied. Over 7 years of data, DENALI THERAPEUTICS has consistently demonstrated commitment to H-1B sponsorship.

Note: These are Labor Condition Applications (LCAs) filed with the Department of Labor, which is a prerequisite for H-1B petitions. The actual number of H-1B petitions filed with USCIS may differ.

DENALI THERAPEUTICS's LCA (Labor Condition Application) denial rate is 0%, with 0 out of 49 applications denied across all years. This translates to a 100.0% certification rate, which indicates how successfully the company prepares and files H-1B applications. A lower denial rate suggests better compliance with Department of Labor requirements, proper wage documentation, and accurate job classification. Prospective H-1B applicants should consider this approval rate alongside other factors like salary, job role, and location when evaluating DENALI THERAPEUTICS as a potential H-1B sponsor.

This is an excellent approval rate, indicating DENALI THERAPEUTICS has strong H-1B sponsorship practices and typically meets DOL requirements. Applicants can feel confident in the company's H-1B track record.

DENALI THERAPEUTICS sponsors H-1B visas for various specialty occupation positions requiring at least a bachelor's degree. Based on 45 certified filings, the most commonly sponsored job titles reflect the company's primary business functions and talent needs. These positions typically require specialized knowledge in fields like technology, engineering, finance, or scientific research. Understanding which roles DENALI THERAPEUTICS most frequently sponsors can help job seekers target their applications effectively.

Most common H-1B job titles at DENALI THERAPEUTICS:

The most frequently sponsored role is Research Scientist with 16 filings at a median salary of $123,518. This is followed by Senior Research Scientist (6 filings) and Clinical Data Manager.

DENALI THERAPEUTICS's H-1B positions are distributed across multiple U.S. locations, with concentration in major metropolitan areas and tech hubs. Geographic distribution often reflects company office locations, client sites, and regional market demands. Location significantly impacts H-1B salary due to varying cost of living and local wage requirements. Understanding where DENALI THERAPEUTICS sponsors H-1B workers can help candidates target specific offices and negotiate appropriate compensation for each market.

Top DENALI THERAPEUTICS H-1B locations:

The largest H-1B hub for DENALI THERAPEUTICS is South San Francisco, CA with 42 filings at a median salary of $138,000. The highest-paying location is Holly Springs, NC at $204,194 median. Salaries range from $130,000 to $204,194 across office locations.

DENALI THERAPEUTICS's median H-1B salary has increased by +8% from FY 2020 ($127,375) to FY 2026 ($138,000). Tracking salary trends over time reveals how DENALI THERAPEUTICS adjusts compensation to remain competitive in the H-1B labor market. Salary growth typically reflects inflation adjustments, increased demand for specialized skills, and evolving prevailing wage requirements. These historical trends can help applicants understand future salary expectations and negotiate appropriately when considering H-1B opportunities at DENALI THERAPEUTICS.

Year-by-year breakdown:

• FY 2022: $128,752 (11 certified)
• FY 2023: $152,041 (6 certified)
• FY 2024: $140,000 (7 certified)
• FY 2025: $158,000 (9 certified)
• FY 2026: $138,000 (4 certified)

DENALI THERAPEUTICS has maintained steady salary growth for H-1B positions over this period.

DENALI THERAPEUTICS primarily files H-1B applications at Wage Level II, accounting for 49% of their filings. DOL wage levels range from Level I (entry-level, 17th percentile of local wages) to Level IV (expert, 67th percentile). Wage level determines both salary requirements and, under recent H-1B rules, lottery selection priority. Higher wage levels receive preference in the H-1B lottery, making DENALI THERAPEUTICS's wage level distribution an important factor for prospective applicants assessing their chances of H-1B selection.

With 93% of positions at Level II or higher, DENALI THERAPEUTICS typically offers competitive wages above entry-level. Higher wage levels receive priority in the H-1B lottery.

DENALI THERAPEUTICS's median H-1B salary of $138,000 is 15% higher than the national H-1B median of $120,000 across all employers and industries. This comparison provides context for evaluating DENALI THERAPEUTICS's competitiveness in attracting H-1B talent. Keep in mind that industry, location, and job function significantly impact salary levels. Tech companies and financial institutions typically offer higher H-1B salaries than other sectors, while salaries in major metros like San Francisco and New York exceed those in smaller markets. Compare DENALI THERAPEUTICS's offerings with similar companies in your field for a more accurate assessment.

DENALI THERAPEUTICS offers above-average H-1B compensation. Combined with their 45 certified filings and 0% denial rate, they demonstrate solid H-1B sponsorship practices.

Recent H-1B rule changes have increased filing fees and introduced wage-level prioritization in the lottery. DENALI THERAPEUTICS files 7% of positions at Level I, which may face more lottery competition under wage-level prioritization rules.

With 45 certified filings, DENALI THERAPEUTICS invests significantly in H-1B sponsorship. The company's 0% denial rate suggests strong compliance with H-1B requirements and documentation standards.

Note: H-1B regulations are subject to change. Fees shown are estimates based on 2024 USCIS fee schedules. Actual costs may vary based on company size, premium processing, and future rule changes.